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为探索博菜霉素性肺炎(BIP)的预测因素,作者测定了39例播散性睾丸癌患者在联合化疗过程中的5项肺功能指标及1项肾功能指标。 39例病人平均年龄为29.6岁,19例有肺转移,25侧为吸烟者,无1例先有肺部疾病。所有病人均接受博菜霉素、长春碱及顺二氢化二氨亚铂3种药物的联合化疗。博莱霉素的用量为每次30mg,于15分钟内静滴,每周1次,共12周。疗程中监测下列指标:①一氧化碳转移因子(Transfer factor of carbon monoxide);②肺泡-毛细血管膜的弥散量;③肺毛细血
To explore predictors of bleomycin-induced pneumonia (BIP), the authors measured 5 lung function parameters and 1 renal function index in 39 patients with disseminated testicular cancer during chemotherapy. The mean age of 39 patients was 29.6 years, 19 had lung metastases, 25 had smokers, and none had first had a lung disease. All patients received the combined treatment of bleomycin, vinblastine and cisplatin plus 3 drugs. Bleomycin dosage for each 30mg, intravenous infusion within 15 minutes, once a week for a total of 12 weeks. The following indicators were monitored during the course of treatment: ① Transfer factor of carbon monoxide; ② Diffusion of alveolar-capillary membrane; ③ Pulmonary capillary