苦参对精子杀伤作用已在实际中证实,但应用在阴道内则需要考虑它对阴道及宫颈的直接损伤,以及机体吸收、排泄及毒性等问题。为此,我们进行了这方面的动物实验观察。材料与方法动物系健康雌性成年小白鼠。苦参避孕栓由中药系药剂教研室制作。取小白鼠24只分两组,实验组每日将药栓放置小白鼠阴道 The effect of Sophora flavescens on sperm killing has been confirmed in practice, but the application of it in the vagina needs to consider its direct damage to the vagina and cervix, as well as the body’s absorption, excretion and toxicity. For this purpose, we conducted animal experiments in this area. Materials and Methods Animal Health Healthy female mice. Sophora flavescens contraceptive suppository is made by the Department of Pharmacy of Traditional Chinese Medicine. 24 mice were divided into two groups. The experimental group placed the drug bolus into the vagina every day.