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本文报道70例妊高征胎盘床活检的组织形态学,并与110例正常妊娠胎盘床活检进行对照。结果显示妊高征胎盘床蜕膜段与蜕-肌段螺旋动脉的病理性改变较正常组增高;妊高征组蜕-肌段螺旋动脉的生理性变化较正常组减少,P<0.001。但国外某些学者认为妊高征普遍存在的特有的急性动脉粥样化却罕见,提示妊高征胎盘床不一定具有特征性的动脉病变。其次,妊高征组半数以上肌层内血管周围有灶性淋巴细胞浸润,与正常组比较有显著差异,可能与细胞免疫有关。
This article reports 70 cases of pregnancy-induced hypertension placenta biopsy histomorphology, and with 110 cases of normal pregnancy placental biopsy control. The results showed that the pathological changes in the placenta bed decidualization segment and the desmoid muscle segment of PIH were higher than those in the normal control group. The physiological changes of the desmoid muscle segment in the PIH group were less than those in the normal group (P <0.001). However, some foreign scholars believe that the prevalence of PIH common unique atherosclerosis is rare, suggesting that PIH placental bed may not have a characteristic arterial disease. Second, more than half of the PIH group had focal lymphocytes infiltration around the blood vessels, which were significantly different from the normal group, which may be related to cellular immunity.