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目的:探讨异甘草酸镁注射液治疗肝病的临床疗效及安全性。方法:将我院2011年12月-2014年1月收治的200例肝病患者随机分为两组,每组100例,其中观察组采取异甘草酸镁注射液治疗,对照组采取复方甘草酸苷注射液治疗,比较两组患者经治疗后的临床疗效及不良反应发生情况。结果:治疗后观察组总有效率为97.00%,对照组为80.00%,观察组明显高于对照组,两组比较差异显著,(P<0.01);观察组不良反应发生率为2.00%,对照组为12.00%,观察组明显低于对照组,两组比较差异显著,(P<0.01)。结论:异甘草酸镁注射液治疗肝病疗效显著,不良反应少,安全性高,值得临床推广应用。
Objective: To investigate the clinical efficacy and safety of magnesium glycyrrhizinate injection in the treatment of liver disease. Methods: 200 cases of liver disease admitted from December 2011 to January 2014 in our hospital were randomly divided into two groups (n = 100 in each group). The observation group was treated with magnesium glycyrrhizinate injection and the control group was treated with compound glycyrrhizin injection The clinical efficacy and adverse reactions of the two groups after treatment were compared. Results: After treatment, the total effective rate was 97.00% in the observation group and 80.00% in the control group, the observation group was significantly higher than the control group, the difference was significant (P <0.01); the incidence of adverse reactions in the observation group was 2.00% Group was 12.00%, the observation group was significantly lower than the control group, the difference between the two groups was significant (P <0.01). Conclusion: Magnesium isrimazole injection in the treatment of liver disease has obvious curative effect, less adverse reactions and high safety, which is worthy of clinical application.