胆囊癌是胆道系统最常见的恶性肿瘤 ,约占全部胆道恶性肿瘤的 64 .7%。我国的胆囊癌发生率在消化系统肿瘤中占第 6位 ,仅次于胃癌、大肠癌、食管癌、肝癌和胰腺癌。胆囊癌在临床上却并不十分常见 ,约占全部癌肿的 0 .8%～ 1 .2 % ,故对于胆囊癌细胞的增殖与凋亡分子机制的研究 Gallbladder cancer is the most common malignant tumor of the biliary tract, accounting for 64.7% of all biliary malignancies. The incidence of gallbladder cancer in China accounted for the sixth in the digestive system tumors, second only to gastric cancer, colorectal cancer, esophageal cancer, liver cancer and pancreatic cancer. Gallbladder cancer is not very common in clinical practice, accounting for about 0.8% ~ 1.2% of all cancers, so the molecular mechanism of gallbladder cancer cell proliferation and apoptosis