氟哌酸(NFLX)属氟喹诺酮类抗菌药物,由于其抗菌谱广,抗菌活性较强,近年来已广泛用于临床。我院1988～1990年用其治疗各种感染600例,并对不良反应进行观察,现报告如下。 1 临床资料 1.1 一般资料本组600例中,男315例,女285例,平均年龄27.8±13.6岁。伤寒456例,呼吸系统、肠道、泌尿系统、腹腔和胆道感染共144例。 1.2 不良反应 600例中,发生消化道反应125例(21％),表现为恶心、上腹不适或灼热感,绝大多数 Norfloxacin (NFLX) is a fluoroquinolone antibacterial drugs, because of its broad antibacterial spectrum, strong antibacterial activity, has been widely used in clinical practice in recent years. Our hospital from 1988 to 1990 with its treatment of various infections in 600 cases, and the adverse reactions were observed, are as follows. 1 Clinical data 1.1 General Information The group of 600 cases, 315 were male and 285 female, with an average age of 27.8 ± 13.6 years. 456 cases of typhoid fever, respiratory system, intestinal tract, urinary system, abdominal and biliary tract infections were 144 cases. 1.2 Adverse reactions 600 cases, the occurrence of gastrointestinal reactions in 125 cases (21%), manifested as nausea, abdominal discomfort or burning sensation, the vast majority