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目的研究老年脑梗塞患者脑血流动力学及脑血流量(CBF)。方法随机选择73例老年及50例非老年患者,同时做TCD及133Xe吸入法测定CBF。结果发现老年组患者TCD主要表现为病灶区血流速度降低,共63例,占86.3%;非老年组则为23例,占46.0%,2组比较,P<0.01;2组血流速度降低均与相应CBF降低呈正相关,在老年组r=0.94,P<0.01,非老年组r=0.88,P<0.01;脑梗塞病灶大则血流速度、CBF降低者多。结论老年脑梗塞患者血流速度降低与脑血流量减少有良好的一致性,TCD可作为评价CBF的有效手段。
Objective To study cerebral hemodynamics and cerebral blood flow (CBF) in elderly patients with cerebral infarction. Methods A total of 73 elderly patients and 50 non-elderly patients were randomly selected. CBF was measured by TCD and 133Xe inhalation simultaneously. The results showed that TCD in the elderly group was mainly manifested as decreased blood flow velocity in the lesion area, 63 cases (86.3%); 23 cases (46.0%) in the non-elderly group, P <0.01; The decrease of blood flow velocity in both groups was positively correlated with the decrease of corresponding CBF, r = 0.94 in the elderly group, P <0.01, r = 0.88 in the non-elderly group, P <0.01; Flow rate, CBF decreased more. Conclusions There is a good consistency between the reduction of blood flow velocity and the decrease of cerebral blood flow in elderly patients with cerebral infarction. TCD can be used as an effective method to evaluate CBF.