补骨脂注射剂临床用于治疗白癜风、秃发、牛皮癣,收到了满意的效果。本文针对注射剂制备过程中所出现的一些问题,在工艺流程及质量控制方面进行了一些探讨。笔者认为:1.制斑素注射剂的制备工艺应以水提醇沉精制滑石地处理为最佳;2.制斑素注射剂可以用分光光度计在237nm波长处测定其总黄酮的含量,以作为该注射剂质量控制的一种手段。 Buguzhi injection has been used clinically to treat vitiligo, baldness, and psoriasis and has received satisfactory results. In this paper, some problems occurred during the preparation of injections were discussed in terms of process flow and quality control. The author believes that: 1. The preparation process of the preparation of spotted pigment should be treated with water extracted alcohol precipitation refining talc to be the best; 2. The preparation of spotting pigment can use spectrophotometer at the wavelength of 237nm to determine its total flavonoid content, as This injection is a means of quality control.