有资料表明梅尼埃病、特发性感音神经性聋和突聋等病人血清中内耳组织 30 k Da蛋白的抗体活性升高 ,Cao(1996 )等人认定此蛋白是周围神经髓鞘糖蛋白P0 ,特异性表达于周围神经系统施旺细胞 ,其氨基酸序列具有种间高度保守性。在内耳 ,P0 蛋白主要在螺旋神经节和螺旋器表达。该作 There are data indicating that the 30 kDa protein in the inner ear tissue of patients with Meniere’s disease, idiopathic sensorineural deafness and sudden deafness has increased antibody activity. Cao (1996) et al. Identified this protein as peripheral nerve myelin glycoprotein P0, specifically expressed in the peripheral nervous system Schwann cells, the amino acid sequence with a high degree of species conservation. In the inner ear, P0 protein is mainly expressed in the spiral ganglion and the spiral. The work