目的:研究分光光度法测定左旋多巴片的含量。方法:在硼砂溶液中,左旋多巴和2,6-二氯醌氯亚胺发生反应,生成荷移络合物。结果:络合物的λ_(max)=496nm,组成比为1:1,表观摩尔吸光系数ε=1.1×10~4 L·mol~(-1)·cm~(-1),线性范围为2.5～23.8μg·mL~(-1),回收率为96.81%～97.59%,RSD 为0.55%～0.60%。结论:应用本方法测定左旋多巴片的含量,得到满意的结果。 Objective: To determine the content of levodopa tablets by spectrophotometry. Methods: In borax solution, levodopa reacted with 2,6-dichloroquinone chloride imine to form charge-transfer complex. Results: The λ max of the complex was 496 nm with the composition ratio of 1: 1 and the apparent molar absorptivity ε = 1.1 × 10-4 L · mol -1 cm -1. The linear range The recoveries ranged from 96.81% to 97.59%. The RSDs ranged from 0.55% to 0.60%. Conclusion: This method was used to determine the content of levodopa tablets, and satisfactory results were obtained.