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表达Vγ9和Vδ2 T细胞受体(TCR)的人类T细胞亚群,称为Vγ9/Vδ2 T细胞。在出生时它只是CD_3~+ T细胞的一小部分,成年后逐渐成为一个主要亚群,占外周血中γδT细胞的70%～90%。它可在某些细菌、病毒和寄生虫的刺激下发生增殖,并在免疫防御中起着重要作用。在体外,它的增殖依赖于辅助细胞的存在但与组织相容性复合体无关。作者用结核杆菌的丙酮沉淀成分(AP-MT)作为刺激抗原,研究Vγ9/Vδ2 T细胞发生增殖时所需的辅助细胞,用免疫磁力分
Human T-cell subsets expressing Vγ9 and Vδ2 T-cell receptors (TCRs), known as Vγ9 / Vδ2 T cells. It is only a small part of CD3 + T cells at birth and gradually becomes a major subpopulation in adulthood, accounting for 70% to 90% of the γδ T cells in the peripheral blood. It can proliferate stimulated by certain bacteria, viruses and parasites and plays an important role in immune defense. In vitro, its proliferation depends on the presence of helper cells but not on the histocompatibility complex. The authors used Mycobacterium tuberculosis acetone precipitation component (AP-MT) as stimulating antigen to study the proliferation of Vγ9 / Vδ2 T cells required helper cells, with immunomagnetic force