浙江省盛产柑桔,时有发生儿童因过量食柑桔致皮肤黄染。近两年在我院门诊发现因食柑桔致皮肤黄染9例,现报告如下。 1.临床资料 本组9例,男6例,女3例,年龄3～7岁,均因皮肤黄染被怀疑为肝炎来我院就诊,其中2例在当地卫生所诊断为“急性肝炎”,给予肝太乐、中医中药等治疗无效。追问病史,患儿最近曾食柑桔约500～1000g/d不等,于食后一周左右皮肤出现黄染,7例食欲下降。查体:黄染累及手掌、足底、前额、鼻翼等处皮肤,巩膜无黄染。无皮肤瘙痒,肝脏无肿大,肝功能正常,尿三胆均阴性。嘱停食柑桔及含胡萝卜素的食物后,多饮水,约1个月余皮肤黄染均自行消退。 2.讨论 胡萝卜素呈黄色,在植物界分布很广,许 Zhejiang Province, rich in citrus, sometimes due to excessive consumption of citrus caused by yellowing of the skin. In the past two years in our hospital found citrus orange caused by skin yellow dye in 9 cases, are as follows. 1. Clinical data The group of 9 patients, 6 males and 3 females, aged 3 to 7 years old, were due to skin yellow dye is suspected of hepatitis to our hospital, of which 2 were diagnosed in the local health clinic as “acute hepatitis” , Given too liver, Chinese medicine and other treatment is invalid. Asked history, children recently eaten citrus about 500 ~ 1000g / d ranging from about 1 week after the skin appear yellow dye, decreased appetite in 7 cases. Physical examination: yellow dye involving the palm, plantar, forehead, nose and other skin, sclera no yellow dye. No skin itching, no enlargement of the liver, normal liver function, urinary three gallbladder were negative. Excuse me to stop eating citrus and carotene-containing foods, drink plenty of water, about 1 month yellow skin subsided spontaneously. 2. Discussion Carotene yellow, widely distributed in the plant kingdom, Xu