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为尽早发现及防治糖尿病并发症,用ELISA双抗体夹心法检测糖尿病患者血浆D—二聚体含量,同时观察血糖的高低与D—二聚体含量的关系,将41例病人组(平均年龄62.3±14.5岁)分为无并发症(17例)、大血管病变(14例)、微血管病变(10例)进行比较。对照组40例(平均年龄59.2±7.3岁)。t检验统计学处理。结果:病人组D—二聚体明显高于对照组,P<0.01;无并发症组与对照组比较无差别,P>0.05;大、微血管病变者显著升高,P<0.01;血糖越高,D—二聚体越升高,我们认为检测糖尿病D—二聚体是糖尿病并发血管病变的诊断指标之一。严格控制血糖、监测D—二聚体对防治糖尿病并发症有一定意义
In order to detect and prevent diabetic complications as soon as possible, the plasma D-dimer level in patients with diabetes mellitus was detected by ELISA. Meanwhile, the relationship between the level of D-dimer and blood glucose level was observed. 41 patients (mean age 62 .3 ± 14.5 years old) were divided into no complications (17 cases), macrovascular disease (14 cases), microvascular lesions (10 cases) were compared. Control group, 40 cases (mean age 59.2 ± 7.3 years). t test statistical treatment. Results: The D-dimer was significantly higher in the patients than in the control group, P <0.01. There was no difference between the non-complication group and the control group (P> 0.05) .01; the higher the blood glucose, the higher the D-dimer. We think that the detection of diabetic D-dimer is one of the diagnostic criteria for diabetic patients with vascular lesions. Strict control of blood glucose, D-dimer monitoring of complications of diabetes prevention has some significance