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对155例恶性肿瘤患者血清的GGT,CP,LD,ALP,α1-AT,AFU,AFP,CEA进行测定。结果:α1-AT测定值除血液病比正常参考值低外,其它癌症组均高于正常参考值的上限,表明α1-AT测定适用于多种癌症的检测。肝癌患者GGT,CP,α-AT,AFU,AFP活性显著升高,阳性率达52~91%。胰头癌除LD,CEA,AFP外其它5项指标升高显著。肺癌组CP,α1-AT,LD活性明显升高,阳性率在62.5~87.5%。消化道癌α1-AT,CEA增加,阳性率为62.3%和14%。鼻咽癌GGT,CP,α1-AT,AFU升高,阳性率分别是67,100,67,67%。乳腺癌CP和α1-AT升高,阳性率为67%。粒细胞白血病LD活性升高非常显著,阳性率为100%。
The serum GGT, CP, LD, ALP, α1-AT, AFU, AFP, and CEA were measured in 155 patients with malignant tumors. RESULTS: The determination value of α1-AT was lower than the normal reference value except for hematological diseases, and other cancer groups were higher than the upper limit of the normal reference value, indicating that the α1-AT assay is suitable for the detection of various cancers. The activity of GGT, CP, α-AT, AFU and AFP in patients with hepatocellular carcinoma was significantly increased, and the positive rate was 52 to 91%. In addition to LD, CEA, AFP, other five indicators of pancreatic head cancer increased significantly. The activities of α1-AT and LD in the lung cancer group were significantly increased, and the positive rate was between 62.5 and 87.5%. Gastrointestinal cancer α1-AT, CEA increased, the positive rate was 62.3% and 14%. Nasopharyngeal carcinoma GGT, CP, α1-AT, AFU increased, the positive rates were 67, 100, 67, 67% respectively. Breast cancer had elevated CP and α1-AT, with a positive rate of 67%. The increase of LD activity in granulocytic leukemia is very significant, with a positive rate of 100%.