目前认为,某些与血栓形成有关的疾病,在血栓形成之前,其体内已存在一种被称为血栓前状态的病理过程,系指其血液有形成分或无形成分的生物化学及流变学的病理性改变。在慢性阻塞性肺疾病(COPD)的病理生理过程中,血栓前状态可促进病人的炎性反应〔1〕,参与血管内皮损伤的发 It is currently believed that some thrombosis-related diseases exist in the body prior to thrombosis, a pathological process known as prothrombotic state, which refers to the biochemistry and rheology of the blood visible or invisible components Pathological changes. In the pathophysiology of chronic obstructive pulmonary disease (COPD), the prothrombotic state can promote the patient’s inflammatory response 〔1〕, involved in the development of vascular endothelial injury