目的　总结Graves病眼病 (内分泌眼病 )的病因和诊治经验。方法　复习相关文献 ,并总结作综述性报道。结果　内分泌眼病占Graver病的 2 5 % ,其表现为浸润性突眼 ,球结膜水肿 ,眼肌麻痹和失明 ;其病因是特异性自身免疫病所致 ,即甲状腺刺激素受体自身抗体 (TRAb)累及甲状腺和眶内组织 ,造成淋巴细胞浸润和炎性反应使视力器官结构改变 ,另外其眶内IgA含量增高 ;治疗上除了口服抗甲状腺药物、激素治疗、眶后照射等外 ,甲状腺全切除术可以降低血中TRAb的滴度而达到治疗目的。结论　Graves病是由自身免疫病所致 ,对内分泌眼病的治疗应尽早实施甲状腺全切除术 Objective To summarize the etiology and diagnosis and treatment of Graves disease (endocrine eye disease). Methods to review the relevant literature, and summarized as a comprehensive report. Results Endocrine eye disease accounted for 25% of Graver’s disease, which manifested as infiltrating exophthalmus, conjunctival edema, ophthalmoplegia and blindness; the cause is specific autoimmune disease caused by thyroid stimulating hormone receptor autoantibodies (TRAb ) Involving the thyroid and orbital tissue, resulting in lymphocyte infiltration and inflammatory response to visual structure changes, in addition to its orbital IgA levels increased; treatment in addition to oral anti-thyroid drugs, hormone therapy, orbital posterior irradiation, the total thyroidectomy Surgery can reduce the titer of blood TRAb for therapeutic purposes. Conclusions Graves’ disease is caused by autoimmune disease, and total thyroidectomy should be performed as soon as possible for the treatment of endocrine eye diseases