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用描述流行病学方法分析2005-2014年缙云县肾综合征出血热(hemorrhagic fever with renal syndrome,HFRS)疫情资料,采用(enzyme-linked immunosorbent assay,ELISA)法对健康人群与鼠类进行HFRS抗体的血清学调查。结果显示,10年共报告HFRS 204例,年均发病率为4.52/10万;2010年死亡2例。全年各月均有发病,呈现11月与7月的双峰型;各乡镇均有病例报告,溪流沿岸乡镇发病率较高;以30~64岁的男性农民为发病的高危人群。健康人群隐性感染率为4.63%,鼠类感染率为13.60%,不同发病率乡镇之间的健康人群感染率及鼠类感染率的差异均有统计学意义(χ~2=7.253、17.579,P<0.05)。缙云县健康人群的免疫力低,鼠类的感染率较高,需加强重点区域、重点人群的监测与防护,以减少HFRS的发生。
The descriptive epidemiological method was used to analyze the epidemic situation of hemorrhagic fever with renal syndrome (HFRS) in Jinyun County in 2005-2014. The HFRS antibody was detected in healthy people and mice by enzyme-linked immunosorbent assay (ELISA) Serological survey. The results showed that a total of 204 cases of HFRS were reported in 10 years, with an average annual incidence of 4.52 / 100,000; in 2010, 2 cases died. Incidences occurred in all the months of the year, presenting a bimodal pattern in November and July. Cases were reported in all towns and townships, with a higher prevalence in villages and towns along stream streams. Male farmers aged 30-64 years were at high risk of developing disease. The prevalence of latent infection in healthy population was 4.63% and the infection rate in rodent was 13.60%. There were significant differences in the infection rate of infection and the infection rate of rodent in township population with different morbidity (χ ~ 2 = 7.253, 17.579, P <0.05). The healthy population of Jinyun County has low immunity and high infection rate of rodents. It is necessary to strengthen the monitoring and protection in key areas and key populations in order to reduce the occurrence of HFRS.