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在体外实验中绞股篮总皂甙(GP)能抑制大鼠肝微粒体自发的和由Fe_-~(2+)-半胱氨酸、Vit C-NADPH和CCl_4诱发的脂质过氧化,其作用强于人参总皂甙。Fe_-~(2+)-半胱氨酸导致大鼠肝微粒体、线粒体膜流动性降低,同时加入GP可防止膜流动性的下降。
In vitro experiments, gypenosides (GP) inhibited lipid peroxidation induced spontaneously in rat liver microsomes and induced by Fe_ (2 +) - cysteine, Vit C-NADPH and CCl_4 The effect is stronger than ginseng total saponin. Fe ~ - ~ (2 +) - cysteine caused rat liver microsomal, mitochondrial membrane fluidity decreased, while adding GP can prevent the decline in membrane fluidity.