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为比较联合使用氨甲喋呤(MTX)和米非司酮(RU486)与单独使用MTX对治疗宫外孕的疗效,进行Ⅱ期临床试验,对Poissy医院在1996年2～11月间的宫外孕患者收集符合联用物药治疗标准者30例(简称联用组)。以非腹腔镜推导结合血清hCG定量水平、阴道B超宫内无孕囊和无任何附件包块,刮宫无绒毛诊断宫外孕。凡血清hCG水平<2000IU/L,且在此水平上有持续异常增加(48h以上增加<50%)则作刮宫术。若hCG≥2000IU/L和B超未见宫内孕囊或宫外孕有心搏者不作刮宫。hCG>10000IU/L、有胎心搏动者除外。在证实宫外孕病变有进展(48h后hCG水平升高)属于进行性
To compare the efficacy of methotrexate (MTX) and mifepristone (RU486) with MTX alone in the treatment of ectopic pregnancy, a phase II clinical trial was conducted in which patients with ectopic pregnancy in Poissy Hospital between February and November 1996 were collected in combination with Drug treatment standards in 30 cases (referred to as the combination group). Non-laparoscopic deduction combined with serum hCG quantitative levels, intrauterine vaginal B intrauterine gestational sac and without any mass, curettage lint-free diagnosis of ectopic pregnancy. Where the serum hCG level <2000IU / L, and in this level there is a sustained abnormal increase (48h more than <50%) for curettage. If hCG â ‰ ¥ 2000IU / L and B did not see intrauterine gestational sac or ectopic pregnancy who do not have curettage curettage. hCG> 10000IU / L, except those with fetal heartbeat. In confirming the progress of ectopic pregnancy lesions (hcG levels after 48h increased) are progressive