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体外受精-胚胎移植(IVF-ET)已用于治疗不明原因、输卵管因素、男性因素及子宫内膜异位症(EM)等引起的不孕。许多学者报道EM患者IVF结局比其他原因不孕者差,其机制可能是卵泡生成障碍、受精能力减弱、胚胎毒素或植入有缺陷。不少研究表明,凋亡小体的发生率可作为评价卵巢功能和卵子质量的指标。本文旨在探讨颗粒细胞膜(简称粒膜)凋亡小体的发生率对进行IVF治疗EM患者卵巢生卵功能的干扰程度。即确定:①粒膜凋亡小体发生率在按修订美国生育协会(AFS)标准分类的各期EM患者之间有无不同。②粒膜凋亡小体发生率在有巧克
In vitro fertilization-embryo transfer (IVF-ET) has been used to treat infertility caused by unknown causes, fallopian tube factors, male factors and endometriosis (EM). Many scholars report that IVF outcomes in EM patients are worse than other causes of infertility. The mechanism may be follicular dysgenesis, weakened fertilization, embryo toxins or implantation defects. Many studies have shown that the incidence of apoptotic bodies can be used as an indicator of ovarian function and egg quality. This article aims to investigate the incidence of apoptotic bodies of granulosa cell membrane (hereinafter referred to as granulosa) on the IVF treatment ovarian ovarian function in patients with disturbance. That is, to determine: ① The incidence of apoptotic bodies in the granulosa membrane according to the revised American Fertility Association (AFS) criteria for the various stages of EM patients with or without any difference. ② the incidence of apoptotic bodies in the presence of chocolate