固体脂质纳米粒（ＳＬＮ）是一种可替代乳剂、脂质体与聚合纳米粒的药物载体系统，其颗粒基质为固体脂质。基质的固体状态可防止所含的活性成分化学降解，可允许在较广的范围内改变药物的释放速率。对于一种成功的ＳＬＮ药物制剂而言，必须保证制备颗粒所用的赋形剂的化学稳定 Solid Lipid Nanoparticles (SLN) is a drug carrier system that can replace emulsions, liposomes and polymeric nanoparticles, and its granular matrix is ​​solid lipid. The solid state of the matrix prevents the contained active ingredients from being chemically degraded, allowing a wide range of drug release rates to be altered. For a successful SLN pharmaceutical formulation, the chemical stability of the excipients used to make the particles must be guaranteed