论文部分内容阅读
目的观察皮下注射低分子肝素钠联合奥扎格雷钠治疗急性脑血栓患者的疗效。方法 120例急性脑血栓患者随机分为治疗组和对照组,每组60例。治疗组采用皮下注射低分子肝素钠(7 d)联合奥扎格雷钠注射液(14 d);对照组采用奥扎格雷钠注射液单药(14 d),观察两组间的疗效差别及治疗前后神经功能缺损程度恢复情况。结果治疗组总有效率91.7%优于对照组76.7%,差异有统计学意义(P<0.01);两组患者治疗后14 d神经功能缺损评分比较差异有统计学意义(P<0.01),治疗期间两组均未出现明显不良反应。结论皮下注射低分子肝素钠联合奥扎格雷钠治疗急性脑血栓效果较单用奥扎格雷钠注射液效果明显,安全性好,值得临床推广应用。
Objective To observe the curative effect of subcutaneous injection of low molecular weight heparin combined with ozagrel on patients with acute cerebral thrombosis. Methods 120 patients with acute cerebral thrombosis were randomly divided into treatment group and control group, 60 cases in each group. The treatment group received subcutaneous injection of low molecular weight heparin (7 d) combined with ozagrel sodium injection (14 d); the control group with ozagrel sodium injection single drug (14 d) to observe the difference between the two groups and treatment Before and after neurological deficit recovery. Results The total effective rate in the treatment group was 91.7%, which was significantly higher than that in the control group (76.7%) (P <0.01). There was significant difference in neurological deficit scores between the two groups 14 days after treatment (P <0.01) During the two groups were no significant adverse reactions. Conclusion Subcutaneous low molecular weight heparin combined with ozagrel sodium in the treatment of acute cerebral thrombosis than ozagrel sodium alone injection effect is obvious, safe and worthy of clinical application.