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目的探讨深部念珠菌感染的常见菌种、好发部位、临床表现及有效的抗真菌药物。方法对我院１９８０年１月～１９９７年６月２８０例住院患者深部念珠菌感染的临床资料进行分析。结果白色念珠菌１４０株占８９．１％。热带念珠菌９株占５．７％，克柔氏念珠菌８株占５．２％。２８０例深部念珠菌感染患者中，老年患者１５６例（５５．７％）。肺部念珠菌感染２１６例中，老年１３０例，中、青年８６例。应用氟康唑治疗的有效率８９．４％。结论近年来深部念珠菌感染的发生率明显增加，以肺部白色念珠菌感染最为常见，老年患者发生率高，氟康唑是有效安全的抗真菌药物。
Objective To investigate the common bacteria species, the predilection sites, clinical manifestations and effective antifungal drugs in deep Candida infections. Methods From January 1980 to June 1997 in our hospital 280 cases of hospitalized patients with deep Candida infection clinical data analysis. Results Candida albicans accounted for 89.1%. Candida tropicalis 9 strains accounted for 5.7%, Candida krusei 8 strains accounted for 5.2%. Among 280 patients with deep Candida infection, 156 cases were elderly (55.7%). 216 cases of lung Candida infection, 130 cases of elderly, middle-aged and young 86 cases. The effective rate of treatment with fluconazole was 89.4%. Conclusion In recent years, the incidence of deep Candida infection increased significantly, the most common pulmonary Candida albicans infection, the high incidence of elderly patients, fluconazole is effective and safe antifungal agents.