棘阿米巴角膜炎是由棘阿米巴原虫感染引起的顽固性、进行性角膜炎,致盲率极高,它常与配戴角膜接触镜、接触污染的水源和角膜外伤等有关。近几年随着角膜接触镜的广泛应用,有关本病感染人数在世界各国逐渐增多,因此引起了眼科学界的广泛重视。我们现就棘阿米巴角膜炎的研究进展加以综述。 Acanthamoeba keratitis is a refractory, progressive keratitis caused by infection with Acanthamoeba, and has a high rate of blindness. It is often associated with exposure to corneal contact lenses, exposure to contaminated water and corneal trauma. In recent years, with the wide application of contact lenses, the number of people infected with this disease is gradually increasing in all countries in the world, which has attracted wide attention from the ophthalmology community. We present the research progress of Acanthamoeba keratitis.