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异烟肼(INH)亦名雷米封,是有效的抗结核药物之一,临床上主要用于治疗和预防结核病。近来临床上用于治疗急性菌痢、肠炎、百日咳、麦粒肿、遗传性舞蹈病、许吉综合征等,也取得较好疗效,使其临床应用范围有所扩大。现将异烟肼的新用途简介如下:一、治疗急性菌痢及肠炎:据报道,INH 和甲氧苄氨嘧啶(TMP)合用治疗急性菌痢678例,取得了与吡哌酸和 TMP 合用治疗急性菌痢相似的临床效果,治愈率98.6%.又有报道,INH 治疗急性菌痢及肠炎56例,总有效率95%.56例中7例在服 INH 之前曾分别服用过痢特灵,合霉素等2~4天未见效,改服 INH 而治愈。江喆报道,用 INH 治疗各种感染性肠炎、菌痢近
Isoniazid (INH), also known as Remy sealed, is one of the effective anti-tuberculosis drugs, and is mainly used clinically to treat and prevent tuberculosis. Recently clinically used for the treatment of acute bacillary dysentery, enteritis, whooping cough, sty, hereditary chorea, Xu Ji syndrome, but also achieved better efficacy, so that its clinical application has been expanded. The new uses of isoniazid are summarized as follows: First, the treatment of acute bacillary dysentery and enteritis: It was reported, INH and trimethoprim (TMP) combined treatment of acute bacillary dysentery 678 cases, made with pipemidic acid and TMP combined Treatment of acute bacillary dysentery similar to the clinical effect, the cure rate was 98.6% .It has also been reported, INH treatment of acute bacillary dysentery and enteritis in 56 cases, the total effective rate was 95% .56 cases in 7 cases before taking INH had taken before the ligation of jatropha , Tetracycline and other 2 to 4 days did not work, change clothes INH and cure. Jiang Zhe reports, with INH treatment of various infectious enteritis, bacillary dysentery