结节病是多系统疾患,但肺脏最常受累。大约70%患者能自行缓解,而1/4～1/5患者有较严重或永久性肺功能损害,其死亡率为5～10%。结节病活动性测定的临床重要意义在于:可作为确定治疗方案的参考依据,并且在观察与治疗过程中作为监测指标。以下仅就近年来国外有关检测结节病活动性的某些指标作一综述。临床指标传统上认为与结节病活动性有关的临床症状与体征包括:体重减轻、发热、出 Sarcoidosis is a multi-system disorder, but the lungs are most commonly affected. Approximately 70% of patients have spontaneous remission, while 1 in 4 to 1 in 5 patients have severe or permanent pulmonary impairment with a mortality rate of 5 to 10%. The clinical significance of sarcoidosis activity determination is that it can be used as a reference basis for the determination of treatment options and as a monitoring indicator during observation and treatment. The following only in recent years abroad on the detection of spermosis activity of certain indicators are reviewed. Clinical Indicators Traditionally, clinical signs and symptoms associated with sarcoidosis are considered to be: weight loss, fever,