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Ⅰ型(胰岛素依赖型)糖尿病是世界人类常见病和致死的重要原因。据报道在欧美某些白人中Ⅰ型糖尿病的发病率平均每年为4.7～39.5/10万,累积发病率(20年)为142～573/10万。目前人们对Ⅰ型糖尿病的认识正在发生变化。过去10年中积累的证据表明Ⅰ型糖尿病在大多数情况下是通过由遗传所决定的(可能由环境因素所触发的)破坏性的自身免疫机制而形成的。
Type I (insulin-dependent) diabetes is a common cause of death in humans and the world. It is reported that in some European and American white people, the incidence of type I diabetes is 4.7 to 39.5 per 100 000 per year on average, and the cumulative incidence (20 years) is 142 to 573 per 100,000. At present, people’s understanding of type 1 diabetes is changing. The evidence accumulated over the past decade shows that type 1 diabetes is in most cases formed through a destructive autoimmune mechanism that is genetically determined (possibly triggered by environmental factors).