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目的：研究脊索样脑膜瘤的临床与病理特征，以提高其早期诊断率。方法：运用组织病理学及免疫组化标记（Ｓ－Ｐ法）对３例脊索样脑膜瘤进行临床病理学和组化（ＰＡＳ）、免疫组化（ＥＭＡ、Ｖｉｍ、Ｓ－１００、ＣＫ）及电镜观察。结果：组织学瘤细胞胞浆内外均见粘液，在粘液基质背景中有成簇或成行的类液滴样细胞，瘤组织中有典型的脑膜上皮漩涡结构，组化及免疫组化示ＰＡＳ（＋）、ＥＭＡ（＋）、Ｖｉｍ（＋）、Ｓ－１００（＋）、ＣＫ（－）；电镜下提示上皮结构并有分泌活性。结论：脊素样脑膜瘤是罕见类型的脑膜瘤，需根据临床病理学、免疫组化及电镜检查方可明确诊断
Objective: To study the clinical and pathological features of chorda-like meningioma in order to improve its early diagnosis rate. Methods: The pathological and immunohistochemical staining (S-P method) was used to evaluate the clinical pathology and histochemistry (PAS), immunohistochemistry (EMA, Vim, S-100, CK) Electron microscopy. Results: Histological tumor cell cytoplasm both inside and outside the mucus, in the mucus matrix background clustered or lineage-like droplet-like cells, tumor tissue typical meningioepithelial swirl structure, histochemistry and immunohistochemistry showed PAS ( +), EMA (+), Vim (+), S-100 (+) and CK (-). CONCLUSIONS: The most common type of meningioma is a rare type of meningioma, which can be diagnosed on the basis of clinicopathology, immunohistochemistry and electron microscopy