目的探讨显微板层角膜切削术（ＭＬＫ）治疗表层角膜病变的可行性。方法以新西兰白兔为实验动物，以切削直径７５ｍｍ、４０ｍｍ和切削深度１２０μｍ、６０μｍ为手术参数，随机将实验动物分为４组，行ＭＬＫ，术后１０天、１、２、３、６个月检测术眼角膜的屈光度、透明度及角膜神经和上皮的组织修复情况。结果术后４个实验组角膜平均上皮化时间３７５天，２～３个月上皮和神经结构基本恢复正常。手术不影响眼屈光和透明度，并可去除角膜的不规则散光。结论浅层显微板层角膜切削术是一种去除前部角膜混浊性病变和不规则性的有效方法 Objective To investigate the feasibility of microcoke keratotomy (MLK) for the treatment of epidermal keratopathy. Methods New Zealand white rabbits were used as experimental animals. The experimental animals were randomly divided into 4 groups according to the cutting diameter of 75 mm, 40 mm and cutting depth of 120 μm, 60 μm. MLK, 10 days, 1, At 3 and 6 months, the corneal refractive power, transparency and tissue repair of corneal nerve and epithelium were detected. Results The average corneal epithelialization time was 375 days after operation in 4 experimental groups. The epithelial and nerve structures returned to normal after 2 ~ 3 months. Surgery does not affect the refractive and transparency of the eye, and can remove the irregular corneal astigmatism. Conclusions Shallow microcolar keratotomy is an effective method to remove the anterior corneal opacity and irregularities