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目的 :探讨世居藏族对快速低氧的适应机制 ,观察长期移居低海拔地区的世居藏族乘飞机进入海拔 3 60 0m高原后ERPN、WBC的变化 ,及同海拔移居适应者和世居者的上述指标 ;方法 :ERPN采用花环法 ,WBC采用常规法 ;结果 :观察组进入高原后最初 3天ERPN均升高 (P <0 .0 5和P <0 .0 1 ) ,第 2天升高尤为明显 ,较平原值升高 3 0 % ;第 7天下降接近平原值和移、世居两组P >0 .0 5 ) ;进入高原前后WBC变化不明显 ,与平原值和移、世居两组接近 (P >0 .0 5 ) ;结论 :世居藏族快速进入高原后极少发生急性高原病 ,红细胞促粒细胞吞噬作用的增强起着一定的作用 ,对低氧的适应机制与细胞水平的早期适应有关。
OBJECTIVE: To explore the adaptation mechanism of native Tibetans to rapid hypoxia, and to observe the changes of ERPN and WBC and the changes of ERPN and WBC after the long-term Tibetan natives migrated to the plateau at altitudes of 3 600 m, Methods: The rosette method was used in ERPN and the routine method was used in WBC. Results: In the first 3 days, ERPN of observation group increased (P <0.05 and P <0.01), and increased on the 2nd day Especially 30% higher than the value of the plain. On the 7th day, the value of the WBC decreased nearly to the value of the plain and shifted to that of the native population (P> 0.05). Before and after entering the plateau, the change of WBC was not obvious, (P> 0.05) .Conclusion: It is very rare that acute Tibetan plateau disease occurs in the native Tibetans and the phagocytosis of erythrocyte granulocyte plays a certain role. The mechanism of adaptation to hypoxia is similar to that of the cells The level of early adaptation related.