无环鸟苷具有高度抗疱疹病毒活性。口服吸收良好,主要经肾排泄。于体内能选择地抑制病毒DNA聚合酶。临床试治疱疹病毒感染、疱疹性角膜炎、带状疱疹感染及巨细胞病毒感染等均有显著效果;对免疫受损患者的此类感染也有效。可以口服、注射、局部及眼用。毒性较小。 Acyclovir has a high anti-herpesvirus activity. Oral absorption of good, mainly by the renal excretion. In vivo can selectively inhibit viral DNA polymerase. Herpes zoster virus infection, herpes keratitis, herpes zoster infection and cytomegalovirus infection are all significant effects; such immunocompromised patients are also effective. Oral, injectable, topical and ophthalmic. Toxicity is small.