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我院儿科自1980年4月至1987年12月门诊治疗小儿癫痫1360例。初诊均应用小剂量苯巴比妥(简称PB),取得了满意的效果。从中随机选出109例用反相高效液相色谱法快速测定微量血中PB的浓度,根据其血浓度监测结果初步分析如下: 方法和资料 1.一般资料:本组共109例。其中男62例,女47例。年龄为8月至15岁。病程为2月至12年。临床表现为癫痫大发作65例,小发作12例,精神运动性发作12例,植物神经发作7
Pediatrics in our hospital from April 1980 to December 1987 outpatient treatment of pediatric epilepsy 1360 cases. Low-dose phenobarbital (referred to as PB) were used in the first visit and achieved satisfactory results. A total of 109 patients were randomly selected by reversed-phase high-performance liquid chromatography for the determination of PB in blood. According to the results of blood concentration monitoring, the results were as follows: 1. General Information: A total of 109 patients were included in this study. There were 62 males and 47 females. The age is from August to 15 years old. The course of the disease is from February to 12 years. Clinical manifestations of epileptic seizures in 65 cases, 12 cases of small seizures, 12 cases of psychomotor seizures, autonomic episode 7