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成人呼吸窘迫综合征(ARDS)相当常见。进一步了解其发病原理,有助于更好地指导临床治疗。一、病理生理学(一)氧合作用障碍ARDS 的特征是严重低氧血症,即使吸入高浓度氧亦难以纠正。绝大多数病例动脉血氧分压(PaO_2)降低,动脉血二氧化碳(PaCo_2)仍正常或降低,说明肺的整体通气仍正常。因此肺泡一动脉氧分压差(A-aDo_2)增大,在呼吸室内空气时,A-aDo_2可>50～60mmHg。当病人有烦燥、心动过速、呼吸困难等表示发病
Adult respiratory distress syndrome (ARDS) is quite common. Further understanding of its pathogenesis, helps to better guide the clinical treatment. First, the pathophysiology (A) Oxygenation disorders ARDS is characterized by severe hypoxemia, even if inhaled high concentrations of oxygen can be difficult to correct. The vast majority of cases of arterial partial pressure of oxygen (PaO_2) decreased, arterial carbon dioxide (PaCo_2) is still normal or decreased, indicating that the overall lung ventilation is still normal. Therefore, alveolar-arterial partial pressure of oxygen (A-aDo_2) increases, in the breathing room air, A-aDo_2> 50 ~ 60mmHg. When the patient is irritable, tachycardia, dyspnea, etc., said the incidence