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对锦州、抚顺、兰州、大连、锦西、南京、上海、大庆、独山子和茂名等十三个炼油厂做了癌症死亡率回顾性队列研究。队列成员51889人,失访1717人(3.31%)。结果表明:页岩型炼油厂队列成员肺癌的SMR显著增高,肺癌与暴露程度间存在着剂量-反应关系。对于煤合成油厂的高暴露区(1971~1988年)的肺癌,通过Logistic回归分析,调整其他环境混淆效应后,其OR值为9.25。石油型炼厂队列成员全癌死亡率增高,在观察期内表现出上升趋势,胃癌、肝癌的SMR分别为1.43和1.51,存在着明显的统计学意义。
A retrospective cohort study of cancer mortality was performed at 13 refineries in Jinzhou, Fushun, Lanzhou, Dalian, Jinxi, Nanjing, Shanghai, Daqing, Dushanzi, and Maoming. There were 51,889 members in the queue and 1,717 people (3.31%) were lost. The results showed that the SMR of lung cancer patients in shale-type refinery cohorts was significantly higher, and there was a dose-response relationship between lung cancer and exposure. For lung cancer in high exposure areas (1971-1988) of coal synthesizing plants, the OR value was 9.25 after adjustment for other environmental confounding effects by Logistic regression analysis. The cancer-bearing mortality rate of oil-based refinery cohort members increased and showed an upward trend during the observation period. The SMR of gastric cancer and liver cancer were 1.43 and 1.51, respectively. There was significant statistical significance.