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目的了解甲型病毒性肝炎(甲肝)在内蒙古自治区乌拉特前旗农牧区11~20岁人群的流行情况。方法采用多阶段抽样的方法,抽取乌拉特前旗农牧区的中、小学生600名,进行甲肝血清流行病学调查。结果收集到符合要求的血清582份,总体抗甲肝病毒抗体(Antibody to Hepatitis A Virus,Anti-HAV)阳性率为14.09%(82/582)。Anti-HAV阳性率女性(16.98%,55/324)高于男性(10.47%,27/258)(χ2=5.03,P<0.05),15~20岁组阳性率(24.53%,26/106)高于11~14岁组(11.76%,56/476)(χ2=11.67,P<0.05),差异均有统计学意义;汉族、蒙古族人群间Anti-HAV阳性率差异无统计学意义(χ2=0.18,P>0.05)。结论乌拉特前旗11~20岁人群Anti-HAV阳性率总体水平低,且不同的年龄段人群Anti-HAV阳性率差异明显,应对类似地区人群接种甲肝疫苗,防止甲肝爆发或流行。
Objective To understand the prevalence of hepatitis A virus (Hepatitis A) among 11-20-year-olds in the pastoral areas of Wulateqianqi in Inner Mongolia Autonomous Region. Methods A multi-stage sampling method was used to extract 600 primary and secondary students in the agricultural and pastoral areas of Wulateqian Banner for the investigation of the hepatitis A seroprevalence. Results A total of 582 serum samples were obtained. The positive rate of Anti-HIV to Antibody to Hepatitis A Virus was 14.09% (82/582). The positive rate of Anti-HAV in female was higher than that of male (10.47%, 27/258) (χ2 = 5.03, P <0.05), while the positive rate was 24.53% (26/106) (11.76%, 56/476) (χ2 = 11.67, P <0.05), and the difference was statistically significant (P <0.05). There was no significant difference in the positive rate of Anti-HAV between Han and Mongolian people (χ2 = = 0.18, P> 0.05). Conclusion The overall positive level of Anti-HAV in 11-20 years old population in Wulateqianqi is low, and the positive rate of Anti-HAV in different age groups is obviously different. Hepatitis A vaccine should be administered to people in similar areas to prevent the outbreak or epidemic of hepatitis A.