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目的分析肝炎肝硬化患者的FibroScan检测值(FS值)与面部色泽变化的相关性,为中医望色判断病情严重程度和病机分析提供客观依据。方法将108例肝炎肝硬化患者划分为代偿期69例,失代偿期39例。运用《肝炎肝硬化临床信息采集表》分别收集两期患者的面色、FS值等,运用SPSS 13.0软件进行描述性统计分析、t检验、单因素方差分析等。结果 108例肝炎肝硬化患者,FS值最小值4.1KPa,最大值75KPa,平均(24.07±18.43)KPa,其中代偿期(16.18±10.06)KPa,失代偿期(38.03±21.50)KPa,两期比较有统计学差异(P<0.01);108例肝炎肝硬化患者正常面色、面红、淡黑、淡黄、淡白、淡青色在代偿期出现比例较高,黝黑、黄黑、青黑色在失代偿期出现比例较高;不同面色的FS值比较差异有统计学意义(P<0.05);面色晦暗程度与FS值变化进行分析,发现面色晦暗程度越重,FS值越来越高,组间比较差异有统计学意义(P<0.01)。结论作为判断病情严重程度的FS值与面部色泽变化有一定的相关性,面色越黑或色泽越暗,FS值越高,而且面色黑在肝硬化多提示血瘀,说明肝硬化病情越重,血瘀越重。
Objective To analyze the correlation between the FibroScan value (FS) and the change of facial color in patients with liver cirrhosis and provide an objective basis for judging the severity and pathogenesis of Chinese medicine. Methods 108 cases of hepatitis cirrhosis patients were divided into compensatory 69 cases, 39 cases of decompensation. The clinical data of hepatitis cirrhosis was used to collect the complexion and FS of two stages of patients respectively. Descriptive statistical analysis, t-test and one-way ANOVA were performed using SPSS 13.0 software. Results In 108 patients with hepatitis cirrhosis, the minimum FS value was 4.1 KPa and the maximum was 75 KPa, with an average of (24.07 ± 18.43) KPa, including compensatory phase (16.18 ± 10.06) KPa, decompensated phase (38.03 ± 21.50) KPa, There were statistically significant differences between the two groups (P <0.01). The normal, reddish, pale, pale yellow, pale white and light cyan in 108 patients with cirrhosis were higher in compensatory phase, dark, yellowish black and cyan (P <0.05). The degree of dullness and the change of FS value were analyzed. The results showed that the more dull the dullness and the higher the FS value , There was significant difference between the two groups (P <0.01). Conclusion As the judgment of the severity of the FS value and facial color change has a certain correlation, the darker the more complexion or darker the color, the higher the FS value, and the complexion of black in cirrhosis and more blood stasis, indicating that the more severe cirrhosis, Blood stasis heavier.