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本文分析了持续释放型钙离子拮抗剂尼卡地平对轻至中度体循环高血压患者的左室(LV)质量(M型超声测定)、二尖瓣血流(多普勒超声测定)和神经体液因子的影响。入选的28例患者(舒张压介于12.7～15.2kPa)经过6周的双盲安慰剂对照处理阶段后,其中24例返回做了各种预定的检查。24例中的13例患者完成了1年的长期试验,构成一个亚组。尼卡地平治疗6周,收缩压和舒张压分别从21±2降至18.9±1.2kPa
In this paper, we analyzed the effects of sustained release nicardipine on left ventricular mass (M-mode ultrasound), mitral valve flow (Doppler ultrasound) and nerves in patients with mild to moderate systemic hypertension Body fluid factors. Twenty-eight of the selected patients (diastolic blood pressure ranged from 12.7 to 15.2 kPa) underwent a double-blind, placebo-controlled phase of treatment six weeks after which 24 patients returned with various scheduled examinations. Thirteen of the 24 patients completed a one-year long-term trial, forming a subgroup. Nicardipine treatment for 6 weeks, systolic and diastolic blood pressure decreased from 21 ± 2 to 18.9 ± 1.2kPa