环戊醚乙炔雌二醇(简称炔雌醚)与氯地孕酮或18甲基炔诺酮等配伍的长效口服避孕药,临床试用每月口服一次即可达到避孕效果。经过不断的改进与减量服用,克服了一些不良反应,成为一种简便有效的避孕药。Greenblatt等对服炔雌醚治疗的妇女子宫内膜进行组织学观察;每天服150微克炔雌醚,累积量至9.5～12毫克时,内膜出现轻度至腺囊型增生过长。 Cyclic pentylethyl ethinyl estradiol (abbreviated as ethinyl estrone) and chlormadinone or 18 norgestrel and other compatible long-acting oral contraceptives, clinical trial oral once a month to achieve the effect of contraception. After continuous improvement and reduce taking, to overcome some of the adverse reactions, as a simple and effective contraceptives. Greenblatt et al on the ethinylestradiol treatment of women with endometrial histological observation; daily dose of 150 micrograms ethinyl estrone, cumulative amount of 9.5 to 12 mg, the endometrial mild to severe cyst hyperplasia.