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为研究局部脑血流(rCBF)断层显像对急性脑外伤的应用价值,探讨 rCBF 的动态变化规律,对10例正常志愿者、40例脑外伤病人伤后1周内进行 rCBF 显像,其中25例1个月后复查,12例3个月再次检查,每例均有同期 CT 对照。除图像分析外还测定正常者两半球各部位以及外伤者病灶处与对侧相应部位 rCBF 比值。结果:①10例正常者脑内两半球灰质的血流分布基本对称;②40例脑外伤 rCBF 断层显像发现病灶89个,CT 发现68个,两者一致58个;③急性脑外伤后 rCBF 明显下降,伤后1个月内增加明显(Q=3.22,P<0.05),3个月仍未恢复正常;④年龄、血肿量及治疗方法对预后有一定影响。故 rCBF 断层显像对反映急性脑外伤后 rCBF 变化及脑神经细胞功能比 CT 灵敏,且可评估其预后。
To investigate the clinical value of regional cerebral blood flow (rCBF) imaging in the diagnosis of acute traumatic brain injury (TBI), the dynamic changes of rCBF were studied. RCBF imaging was performed in 10 normal volunteers and 40 traumatic brain injury patients within 1 week after injury 25 cases were reviewed after 1 month, and 12 cases were checked again 3 months later. Each case had concurrent CT control. In addition to the image analysis, the rCBF ratio of the two parts of the normal hemisphere and the corresponding parts of the lesion at the contralateral side was also determined. Results: ①The distribution of blood flow in the two hemispheric gray matter in 10 normal subjects was basically symmetrical. ②The rCBF in 40 patients with traumatic brain injury was found in 89 lesions and 68 in CT, which were identical with 58. ③ The rCBF decreased significantly after traumatic brain injury , Significantly increased within 1 month after injury (Q = 3.22, P <0.05), and remained normal after 3 months. (4) Age, hematoma volume and treatment methods had some effects on prognosis. Therefore, rCBF tomography to reflect changes in rCBF after acute traumatic brain injury and brain function than sensitive to CT, and can assess the prognosis.