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补肾壮阳液急性毒性实验,口服最大耐受量为40g/kg.未见毒性症状。大鼠长期毒性实验灌胃给药20gl/Kg、10g/lKg和Sg/kg,连续4周,各组无动物死亡,动物外观、休重增长,血象、肝骨功能及各脏器指数与对照组无异。病捡报告高剂士组有3只大鼠部分肝细胞胞浆疏松化和气球样变,但留存动物停药10d后,病检均正常。提示补肾壮阳液临床口服用药安全范围较大。
Kidney impotence liquid acute toxicity test, the maximum oral tolerance of 40g/kg. No symptoms of toxicity were seen. Long-term toxicity experiments in rats were given by gavage at 20gl/Kg, 10g/lKg, and Sg/kg. For 4 consecutive weeks, no animal died in each group. The appearance and weight of the animals increased, and the hemogram, hepatic function and various organ indexes were compared with the control. The group is no different. The sickness group reported that in the high-dosage group, hepatocyte cytoplasmic laxification and balloon-like changes were observed in 3 rats. However, after the animals were discarded for 10 days, the disease tests were normal. Tips Bushen Zhuangyang fluid clinical oral administration of a larger range of safety.