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目的:评价不同剂量舒芬太尼对产妇分娩中镇痛作用。方法:选取2015年6月—2016年6月间在医院产科分娩的产妇80例;按给药剂量的不同将其分为舒芬太尼低剂量组(0.2μg/m L)28例、中剂量组(0.4μg/m L)25例和高剂量组(0.6μg/m L)27例,比较3组患者用药前和用药后(30和60 min)在不同时间点按视觉模拟评分法(VAS)评分值,以及第一产程和第二产程分娩时间和不良反应的发生率。结果:中剂量组产妇的VAS评分值与低剂量组和高剂量组产妇VAS评分值经2组间比较其差异无统计学意义(P>0.05);用药30和60 min时VAS评分值均优于同组用药前(P<0.05);中剂量组产妇第一产程所需时间优于低剂量组和高剂量组(P<0.05);中剂量组产妇第二产程所需时间与低剂量组和高剂量组比较其差异无统计学意义(P>0.05);中剂量组产妇用药期间不良反应的发生率明显低于高剂量组(P<0.05),但与低剂量组比较其差异无统计学意义(P>0.05)。结论:采用中剂量舒芬太尼对产妇分娩中镇痛作用的临床疗效优于低剂量组和高剂量组,产妇的第二产程所需时间均优于第一产程所需时间。
OBJECTIVE: To evaluate the analgesic effects of sufentanil at different doses on labor. Methods: Totally 80 maternal obstetrics and gynecology patients were delivered in the hospital from June 2015 to June 2016. According to the different doses, 28 sufentanil low dose group (0.2 μg / m L) 25 patients in the dose group (0.4μg / mL) and 27 patients in the high dose group (0.6μg / mL). The visual analogue scale was used before and after treatment (30 and 60 min) VAS) score, as well as the first and second stages of labor time and incidence of adverse reactions. Results: There was no significant difference between the two groups in VAS score of middle-dose group and VAS score of low-dose group and high-dose group (P> 0.05) (P <0.05). The time required for the first stage of labor in the middle-dose group was better than that in the low-dose group and the high-dose group (P <0.05). The time required for the second stage of labor was lower in the middle-dose group than in the low-dose group (P> 0.05). The incidence of adverse reactions in the middle dose group was significantly lower than that in the high dose group (P <0.05), but there was no significant difference between the low dose group and the low dose group Significance (P> 0.05). Conclusion: The middle-dose sufentanil is superior to the low-dose group and high-dose analgesia in the delivery of labor, the time required for the second stage of labor is better than that of the first stage of labor.