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目的:观察高频电波刀(LEEP)联合重组人干扰素α-2b凝胶治疗宫颈病变的疗效及并发症情况。方法:选取116例病例随机分为两组,对照组55例和观察组61例。观察组实施LEEP刀联合干扰素凝胶治疗,对照组LEEP术前术后均不用干扰素凝胶。观察两组治愈率、愈合时间及术后并发症发生情况。结果:观察组治愈时间(5.2±1.8)周短于对照组(8.2±1.2)周(P<0.05),观察组并发症发生率6.56%低于对照组的29.09%,组间比较,差异具有统计学意义(P<0.05)。结论:LEEP术后联合使用重组人干扰素α-2b凝胶治疗宫颈病变有助于创面愈合,降低并发症发生率。
Objective: To observe the curative effect and complications of high frequency electrosurgical knife (LEEP) combined with recombinant interferon α-2b gel in the treatment of cervical lesions. Methods: One hundred and sixty-six cases were randomly divided into two groups: control group (55 cases) and observation group (61 cases). The observation group received LEEP knife combined with interferon gel treatment, control group LEEP preoperative and postoperative without interferon gel. The cure rate, healing time and postoperative complications of the two groups were observed. Results: The curative time in observation group (5.2 ± 1.8) was shorter than that in control group (8.2 ± 1.2) weeks (P <0.05). The incidence of complications in observation group was 6.56% lower than that in control group (29.09%). Statistical significance (P <0.05). Conclusion: LEEP combined with recombinant human interferon α-2b gel treatment of cervical lesions help wound healing and reduce the incidence of complications.