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临床医生常给支气管哮喘病人伍用氨茶碱和复方新诺明。我们在氨茶碱的血浓监测中发现:复方新诺明严重干扰原有的氨茶碱紫外测定法。为给临床提供两药伍用时氨茶碱血药浓度的数据、保证其在治疗中安全、有效,我们着手建立了双波长紫外分光光度法以测定氨茶碱的血药浓度。实验部分
Clinicians often use aminophylline and cotrimoxazole for patients with bronchial asthma. We in the aminophylline blood concentration monitoring found: cotrimoxazole serious interference with the original aminophylline UV determination. To provide clinical data on the concentration of aminophylline in two drugs to ensure its safety and effectiveness in treatment, we set out to establish a dual-wavelength UV spectrophotometry to determine the plasma concentration of aminophylline. Experimental part