丙氟哌酸(ciprofloxacin,简称CIP)是新一代喹诺酮氟化物,结构与萘啶酸相似。CIP主要作用机制是抑制细菌的脱氧核糖核酸旋转酶。CIP抗菌谱广,在体外,大多数革蓝氏阴性菌对CIP有很高的敏感性,许多革蓝氏阳性菌对CIP敏感或中度敏感。与其它广谱抗菌药不同的是,CIP口服或静注均有效。目前已对CIP进行了广泛的口服临床研究,它在大多数组织和体液中可达到至少相当于体外最低抑菌浓度。经口服和静注临床 Ciprofloxacin (Ciprofloxacin, referred to as CIP) is a new generation of quinolone fluoride, the structure similar to nalidixic acid. The main mechanism of action of CIP is bacterial DNA dehydrogenase. CIP antibacterial spectrum wide, in vitro, most of the gram-negative bacteria CIP has a high sensitivity, many leather-blue-positive bacteria sensitive to CIP or moderately sensitive. Unlike other broad-spectrum antibacterials, CIP is effective either orally or intravenously. A wide range of oral clinical studies have been conducted on CIP, which is at least equivalent to the minimum inhibitory concentration in vitro in most tissues and body fluids. Oral and intravenous injection of clinical