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药物引起的淋巴结肿胀极少,本文以苯妥英钠为重点进行讨论。一、抗痉挛剂苯妥英钠是常用于小儿痉挛性疾病的药物,其副作用有血小板减少、黄疸、蛋白尿、眩晕、复视、便秘、齿龈肿胀、系统性红斑狼疮样症状、恶性大疱性多形红斑等,很少发生淋巴结肿胀。Li等报告在儿科恶性淋巴瘤中有服苯妥英钠历史的,何杰金病占1.0%,非何杰金占0.3%。一般的药物所致淋巴结肿胀,常伴发热和发疹等
Drug-induced lymph node swelling is minimal, this article focuses on phenytoin sodium for discussion. First, anticonvulsant phenytoin sodium is commonly used in pediatric spastic disease drugs, its side effects are thrombocytopenia, jaundice, proteinuria, dizziness, diplopia, constipation, swollen gums, systemic lupus erythematosus-like symptoms, malignant bullous more Erythema, rarely lymph node swelling. Li et al reported that in patients with pediatric malignant lymphoma with phenytoin sodium history, Hodgkin’s disease accounted for 1.0%, non-Hodgkin accounting for 0.3%. General drug-induced lymphadenopathy, often accompanied by fever and rash