免疫球蛋白类(Igs)是由B细胞和浆细胞产生的一类蛋白质,是组成免疫系统的体液部分。Igs可分为五大类IgG、A、M、D和E。Igs在临床上可用于肌注和静注,但肌注有很多局限。如肌注需4～7d才能达到有效的血液浓度。最大剂量还受肌肉大小和疼痛的限制,肌肉贮存的Igs可能因蛋白水肿而减少。最近,静脉内免疫球蛋白(IVIgs) Immunoglobulins (Igs) are a class of proteins produced by B cells and plasma cells that form the body fluid part of the immune system. Igs can be divided into five major categories of IgG, A, M, D and E. Igs clinically available for intramuscular and intravenous injection, but there are many limitations of intramuscular injection. Such as intramuscular injection required 4 ~ 7d in order to achieve effective blood concentration. The maximum dose is also limited by muscle size and pain, and muscle stored Igs may decrease due to protein edema. Recently, intravenous immunoglobulin (IVIgs)