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目的探讨复发性上皮性卵巢癌的诊断及治疗方法。方法回顾性分析45例复发性上皮性卵巢癌患者的临床资料,全部手术标本经过病理检查证实,比较再次手术联合化疗与单纯化疗患者的生存率。结果 45例中,初次手术时,临床分期Ⅰ、Ⅱ期14例(31.1%),Ⅲ、Ⅳ期31例(68.9%)。27例再次手术且术后联合化疗,与18例单纯化疗患者的生存率比较,差异无统计学意义(P>0.05)。结论再次手术联合化疗与单纯化疗患者生存率相近。
Objective To investigate the diagnosis and treatment of recurrent epithelial ovarian cancer. Methods The clinical data of 45 patients with recurrent epithelial ovarian cancer were retrospectively analyzed. All the surgical specimens were confirmed by pathology. The survival rates of patients who underwent reoperation combined with chemotherapy and chemotherapy alone were compared. Results Of the 45 cases, 14 cases (31.1%) had stage I and II clinical stage, and 31 cases (68.9%) had stage III and IV clinical stage. There was no significant difference in survival rate between the 27 cases undergoing reoperation and postoperative combined chemotherapy and the 18 cases with chemotherapy alone (P> 0.05). Conclusions Survival rates of reoperation combined with chemotherapy are similar to those of chemotherapy alone.