1985年1月2日在法国坎佩尔医院收治了一名57岁的男性病人,因呼吸困难伴有心血管衰竭而入院。生物学检查示多核白细胞增多;病人有很稀的腹泻,且便血。经抗菌素治疗3天后即好转。胃纤维镜检查有细小的溃疡,直肠乙状结肠镜检在直肠和乙状结肠交接处有许多平的溃疡。病理解剖学检查显示表面带有纤维蛋白白细胞渗出物、毛细管扩张的炎性肉芽肿。所有切片的平面上都 On January 2, 1985, a 57-year-old male patient admitted to Quimper Hospital in France was admitted to hospital for treatment of dyspnea associated with cardiovascular failure. Biological examination showed polycythemia white blood cells; patients have very rare diarrhea, and hematochezia. After 3 days of antibiotic treatment improved. Gastric microscopy with small ulcers, rectosigmoidoscopy in the rectum and sigmoid junction with a lot of flat ulcers. Pathological anatomical examination revealed fibrin leukocyte exudate on the surface, telangiectasia, inflammatory granuloma. All slices are on the plane