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虽然脑转移者全脑放疗(WBRT)有益,但首程WBRT后发生进行性脑转移再照射的作用有争论,且资料不多。1975～1993年于Mayo Clinic对2658例做了WBRT,其中86例因其神经学征象恶化和/或影像学有进行性脑转移而做了再照射,以此作为分析的基础,男52例,女34例,中数年龄58岁(31～81岁)。原发癌以乳房(31例)及肺(31例)最多,从诊断原发癌到诊断脑转移的中数期为15个月,50例(58％)亦有颅外转移。多发性脑转移47例,单发性脑转移39例。影像学
Although brain metastases with whole brain radiation (WBRT) is beneficial, the role of progressive brain metastases and re-irradiation after the first-pass WBRT is controversial and not informative. WBRT was performed on 2658 patients at Mayo Clinic from 1975 to 1993, of which 86 were re-irradiated as a result of deterioration of neurological signs and / or progressive brain metastases of imaging. Based on this, 52 patients were male, Female 34 cases, the median age of 58 years (31 to 81 years old). Primary breast cancer (31 cases) and lung (31 cases) up from the diagnosis of primary cancer to diagnosis of brain metastasis in the median period of 15 months, 50 cases (58%) also have extracranial metastases. 47 cases of multiple brain metastases, 39 cases of solitary brain metastases. Videography