答:半合成青霉素,包括新青霉素类(如苯唑青霉素、氯唑青霉素等)和广谱青霉素(如氨苄青霉素、羧苄青霉素等),在应用前均需进行皮肤过敏试验。不论何种青霉素均可用青霉素G溶液(200～500单位/ml),并按青霉素G的皮试方法进行。这是由于青霉素G和半合成青霉素只是在侧链上有区别,它们的母核和致敏原——青霉烯酸蛋白和青霉噻唑蛋白在组成上相同(或极为近似)。青霉素G和各种半合成青霉素之间存 A: Semi-synthetic penicillin, including new penicillins (such as oxacillin, penicillin, etc.) and broad-spectrum penicillin (such as ampicillin, carbenicillin, etc.), are required to be applied before the skin allergy test. Penicillin G solution (200-500 units / ml) can be used regardless of the type of penicillin, and the skin test of penicillin G is performed. This is because penicillin G and semisynthetic penicillins differ only in their side chains, and their parent nucleus and the allergen-penicillin protein and the penicillin-zo protein are identical in composition (or very similar in composition). Penicillin G and a variety of semi-synthetic penicillin deposit between